Gastroenteritis
Loose Stools
Contagious causes: Shigella, Giardia, Salmonella, Rotavirus, Clostridium, Staphylococcus aureus
- Rapid onset, elevated temperature, increased bowel sounds
Request stool tests for ova and parasites, culture, white blood cells, and complete blood count.
Use anti-nausea medications, pain relievers, and medications to reduce bowel activity. - Examples: Lomotil, Levsin, Reglan
Follow a clear fluid diet.
Gastritis
Stomach Inflammation
- Triggers: NSAIDs, alcohol, corticosteroids, contaminated food
- Acute Symptoms: Nausea, vomiting, diarrhea, upper abdominal discomfort, loss of appetite
- Chronic Symptoms: Ulcer formation, bleeding, anemia, risk of peritonitis
- Pain Relief: Often improves with eating
- Onset: Can be sudden or develop gradually
- Management:
- Rule out cardiac causes
- Possible use of a nasogastric tube (NGT)
- Keep patient NPO (nothing by mouth)
- Administer anti-nausea medications
- Use H2 receptor antagonists and proton pump inhibitors (PPIs)
Upper GI Bleed
- Main Cause: Bleeding ulcers (responsible for about two-thirds of cases)
- Other Triggers: Alcohol consumption
- Symptoms:
- Vomiting bright red blood or black, tarry stools (melena) due to blood interacting with stomach acid
Ulcer
Discomfort may worsen with eating or during fastingDuodenal ulcers: Pain typically occurs after meals, with potential bleeding but usually no vomiting of blood
Management:
- Use of antacids, antiemetics, and pain relievers
- Dietary Adjustments:
- Follow a bland diet
- Opt for low-fiber foods to avoid irritation
Lower GI Bleed
- Common Causes: Ulcerative colitis, tumors, polyps, cecal ulcers, ruptured hemorrhoids, diverticular bleeding
- Symptom: Bright red blood per rectum (BRBPR)
- Treatment:
- Fluid resuscitation
- Possible surgical intervention
Bowel Obstruction
- Potential Causes: Severe constipation, scar tissue (adhesions), tumors, bowel paralysis (ileus), telescoping bowel (intussusception), twisted intestine (volvulus)
- Risk Factor: History of abdominal surgery
- Symptoms: Signs of sepsis, abdominal tightness, vomiting
- Management:
- Use of a nasogastric tube (NGT)
- Keep patient NPO
- Intravenous fluids (IVF)
- Surgery may be required
GERD (Gastroesophageal Reflux Disease)
- Symptoms: Burping, burning sensation, feeling of a lump in the throat
- Treatment:
- Proton pump inhibitors (PPIs), H2 receptor antagonists, GI cocktail
- Lifestyle Modifications:
- Avoid spicy foods, caffeine, and peppermint
- Consider weight loss and quitting smoking
- Additional Notes:
- Can worsen asthma symptoms
- Alendronate (Fosamax) can irritate the esophagus; patients should sit upright for at least 30 minutes after taking it
- Treatment:
Pyloric Stenosis
- Location: Lower stomach outlet is narrowed or blocked
- Main Symptom: Forceful vomiting
- Physical Exam: May feel an olive-shaped mass in the abdomen
Pancreatitis
- Causes: Gallstones, excessive alcohol consumption
- Pain Characteristics:
- Sharp, deep pain in the left upper quadrant (LUQ)
- Often starts suddenly
- May be accompanied by vomiting
- Can have wet lung sounds in the lower left lung (LLL)
- Pain Characteristics:
Cholecystitis
- Possible Symptom: Yellowing of the skin or eyes (jaundice)
- Physical Exam Sign: Murphy’s sign – pain on inhalation while pressing on the upper right abdomen
Appendicitis
- Pain Location: Lower right abdomen (RLQ), worsens with movement
- Pain starts around the belly button and moves to the RLQ within 24 hours
- Physical Exam Signs:
- Psoas sign: Patient lies on their left side with legs straight. Examiner extends the patient’s right thigh backward.
- Markle sign: Pain felt when the patient stands on tiptoes and then drops to their heels, jarring the body.
- Rovsing sign: Pressing on the lower left abdomen (LLQ) causes pain in the RLQ.
- McBurney’s Point: Pain located two-thirds of the way between the belly button and the front of the hip bone.
Diverticulitis
- Pain Location: Often described as “appendicitis on the wrong side” because the pain is in the lower left abdomen (LLQ) instead of the RLQ
- More common in older adults (over 50)
- Pain is usually dull and aching
- Possible Symptom: Blood in the stool
- Treatment Options:
- Augmentin
- Immediate Release (IR): 875 mg every 8-12 hours for 4-10 days
- Extended Release (ER): 2,000 mg every 12 hours for 4-10 days
- Ciprofloxacin: 500 mg every 12 hours for 7-10 days
- Combined with Metronidazole: 500 mg every 8 hours for 7-10 days
- Augmentin
Summary of Conditions Affecting the Lower Abdomen
DEFINITION
- UC – Inflammation limited to the large intestine and rectum
- Crohn’s – Chronic inflammation impacting scattered areas throughout the digestive tract, from mouth to anus
- IBS – A functional disorder affecting bowel movements without structural damage
- Celiac Disease – Autoimmune response triggered by gluten consumption
Anatomical Distribution
- UC – Affects only the colon
- Crohn’s – Can affect any part of the GI tract; has skip lesions
- IBS – Affects the colon
- Celiac Disease – Primarily affects the small intestine
Presentation
- UC – Bloody diarrhea, proctitis, tenesmus, weight loss
- Crohn’s – Alternating diarrhea and constipation, crampy or steady abdominal pain, perianal issues (fistulas, ulcers, skin tags), weight loss
- IBS – Recurrent crampy abdominal pain relieved by defecation, no weight loss
- Celiac Disease –
- Infancy: Failure to thrive
- Older children: Delayed growth, malnutrition
- Adults: Variable symptoms, possible weight loss, nutrient deficiencies, higher osteoporosis risk
Histology
- UC – Mucosal inflammation, crypt distortion, cryptitis, crypt abscesses, loss of goblet cells
- Crohn’s – Inflammation in the submucosa or full thickness, deep ulcers, fistulas, patchy changes, granulomas
- IBS – Normal histology
- Celiac Disease – Subtotal villous atrophy
Risk Factors
- UC – Equal in males and females, ex-smokers, HLA-DR103
- Crohn’s – Equal in males and females, higher risk in Ashkenazi Jews, CARD 15/NOD-2 mutation
- IBS – More common in young females, possible history of PTSD, anxiety, or previous gastroenteritis
- Celiac Disease – More common in females, associated with autoimmune disorders (HLA-linked), insulin-dependent diabetes, thyroid disorders
IBS
- A condition related to gastrointestinal motility and spasms
- Elevated ESR
- HIGH FIBER DIET recommended
- Associated with mental health issues like depression and anxiety
Treatment
- Mesalamine suppositories: for mild to moderate ulcerative colitis or Crohn’s disease
- Oral sulfasalazine: for inflammatory bowel diseases
- Left-sided ulcerative colitis: treatment involves a combination of oral and rectal aminosalicylates
Crohn’s Disease
Characterized by abdominal pain, diarrhea, and weight loss
- Affects all layers of the bowel (unlike UC, which only impacts the mucosa and submucosa)
- Can involve the entire gastrointestinal tract and presents with skip lesions
Bone Density Changes in Celiac Disease
Low Bone Density:
- Common in young females and older individuals of both sexes
Normal Bone Density:
- Seen in young men and middle-aged adults
Diets by Diagnosis
- IBS: Avoid sorbitol (which causes gas bubbles) and refrain from drinking water with meals
- Esophagitis: Steer clear of spicy foods, all alcoholic beverages, and opt for small, frequent meals
- GERD: Stick to small, low-fat meals
- Pancreatitis: Avoid alcohol and caffeine
- Cholecystitis: Follow a low-fat diet
Esophageal Varices
Portal hypertension due to cirrhosis leads to congestion
- Symptoms: Dull pain, signs of hemorrhage
- Treatment: Vitamin K, vasopressors, octreotide (Sandostatin)
Mallory-Weiss Tear
Tear in the esophagus caused by forceful vomiting
- Up to 70% of cases linked to heavy alcohol use, and it can also occur in individuals with bulimia
- Increased risk of severe bleeding when combined with esophageal varices